ChloroquineV1, Main, Exploration, bibRecord, 002C02

Immunoliposomes in vivo.

Identifieur interne : 002C02 ( Main/Exploration ); précédent : 002C01; suivant : 002C03

Immunoliposomes in vivo.

Auteurs : M H Vingerhoeds [Pays-Bas] ; G. Storm ; D J Crommelin

Source :

ImmunoMethods [ 1058-6687 ] ; 1994.

RBID : pubmed:7820456

Descripteurs français

KwdFr :
- Amphotéricine B (administration et posologie), Animaux, Anticorps monoclonaux (administration et posologie), Antinéoplasiques (administration et posologie), Biodisponibilité, Candidose (traitement médicamenteux), Cavité péritonéale, Chloroquine (administration et posologie), Essais cliniques comme sujet, Humains, Immunoconjugués (administration et posologie), Immunoconjugués (pharmacocinétique), Immunoconjugués (usage thérapeutique), Injections veineuses, Liposomes (administration et posologie), Liposomes (pharmacocinétique), Noeuds lymphatiques (métabolisme), Paludisme (traitement médicamenteux), Plasmodium berghei, Poumon (métabolisme), Préparation de médicament, Rats, Répartition dans les tissus, Souris, Tumeurs (traitement médicamenteux), Vecteurs de médicaments, Évaluation préclinique de médicament.
MESH :
- administration et posologie : Amphotéricine B, Anticorps monoclonaux, Antinéoplasiques, Chloroquine, Immunoconjugués, Liposomes.
- métabolisme : Noeuds lymphatiques, Poumon.
- pharmacocinétique : Immunoconjugués, Liposomes.
- traitement médicamenteux : Candidose, Paludisme, Tumeurs.
- usage thérapeutique : Immunoconjugués.
- Animaux, Biodisponibilité, Cavité péritonéale, Essais cliniques comme sujet, Humains, Injections veineuses, Plasmodium berghei, Préparation de médicament, Rats, Répartition dans les tissus, Souris, Vecteurs de médicaments, Évaluation préclinique de médicament.

English descriptors

KwdEn :
- Amphotericin B (administration & dosage), Animals, Antibodies, Monoclonal (administration & dosage), Antineoplastic Agents (administration & dosage), Biological Availability, Candidiasis (drug therapy), Chloroquine (administration & dosage), Clinical Trials as Topic, Drug Carriers, Drug Compounding, Drug Evaluation, Preclinical, Humans, Immunoconjugates (administration & dosage), Immunoconjugates (pharmacokinetics), Immunoconjugates (therapeutic use), Injections, Intravenous, Liposomes (administration & dosage), Liposomes (pharmacokinetics), Lung (metabolism), Lymph Nodes (metabolism), Malaria (drug therapy), Mice, Neoplasms (drug therapy), Peritoneal Cavity, Plasmodium berghei, Rats, Tissue Distribution.
MESH :
- chemical , administration & dosage : Amphotericin B, Antibodies, Monoclonal, Antineoplastic Agents, Chloroquine, Immunoconjugates, Liposomes.
- drug therapy : Candidiasis, Malaria, Neoplasms.
- metabolism : Lung, Lymph Nodes.
- chemical , pharmacokinetics : Immunoconjugates, Liposomes.
- chemical , therapeutic use : Immunoconjugates.
- Animals, Biological Availability, Clinical Trials as Topic, Drug Carriers, Drug Compounding, Drug Evaluation, Preclinical, Humans, Injections, Intravenous, Mice, Peritoneal Cavity, Plasmodium berghei, Rats, Tissue Distribution.

Abstract

Attachment of antibodies to the surface of liposomes was performed to confer specificity for a certain cell or organ expressing the targeted antigenic determinant. These so-called immunoliposomes are expected to be applied as targeted drug carriers. In this article, the literature concerning in vivo studies of the targeting of immunoliposomes to various sites in the body is reviewed. The anatomical, physiological, and pathological constraints and current progress are described. Moreover, perspectives on the therapeutic feasibility of this drug targeting system are discussed.

DOI: 10.1006/immu.1994.1028
PubMed: 7820456

Affiliations:

Le document en format XML

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<term>Antineoplastic Agents (administration & dosage)</term>
<term>Biological Availability</term>
<term>Candidiasis (drug therapy)</term>
<term>Chloroquine (administration & dosage)</term>
<term>Clinical Trials as Topic</term>
<term>Drug Carriers</term>
<term>Drug Compounding</term>
<term>Drug Evaluation, Preclinical</term>
<term>Humans</term>
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<term>Immunoconjugates (pharmacokinetics)</term>
<term>Immunoconjugates (therapeutic use)</term>
<term>Injections, Intravenous</term>
<term>Liposomes (administration & dosage)</term>
<term>Liposomes (pharmacokinetics)</term>
<term>Lung (metabolism)</term>
<term>Lymph Nodes (metabolism)</term>
<term>Malaria (drug therapy)</term>
<term>Mice</term>
<term>Neoplasms (drug therapy)</term>
<term>Peritoneal Cavity</term>
<term>Plasmodium berghei</term>
<term>Rats</term>
<term>Tissue Distribution</term>
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<term>Animaux</term>
<term>Anticorps monoclonaux (administration et posologie)</term>
<term>Antinéoplasiques (administration et posologie)</term>
<term>Biodisponibilité</term>
<term>Candidose (traitement médicamenteux)</term>
<term>Cavité péritonéale</term>
<term>Chloroquine (administration et posologie)</term>
<term>Essais cliniques comme sujet</term>
<term>Humains</term>
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<term>Immunoconjugués (pharmacocinétique)</term>
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<term>Injections veineuses</term>
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<term>Liposomes (pharmacocinétique)</term>
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<term>Paludisme (traitement médicamenteux)</term>
<term>Plasmodium berghei</term>
<term>Poumon (métabolisme)</term>
<term>Préparation de médicament</term>
<term>Rats</term>
<term>Répartition dans les tissus</term>
<term>Souris</term>
<term>Tumeurs (traitement médicamenteux)</term>
<term>Vecteurs de médicaments</term>
<term>Évaluation préclinique de médicament</term>
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<term>Chloroquine</term>
<term>Immunoconjugates</term>
<term>Liposomes</term>
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<term>Chloroquine</term>
<term>Immunoconjugués</term>
<term>Liposomes</term>
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<term>Malaria</term>
<term>Neoplasms</term>
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<term>Lymph Nodes</term>
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<term>Poumon</term>
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<term>Liposomes</term>
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<term>Paludisme</term>
<term>Tumeurs</term>
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<keywords scheme="MESH" xml:lang="en"><term>Animals</term>
<term>Biological Availability</term>
<term>Clinical Trials as Topic</term>
<term>Drug Carriers</term>
<term>Drug Compounding</term>
<term>Drug Evaluation, Preclinical</term>
<term>Humans</term>
<term>Injections, Intravenous</term>
<term>Mice</term>
<term>Peritoneal Cavity</term>
<term>Plasmodium berghei</term>
<term>Rats</term>
<term>Tissue Distribution</term>
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<term>Biodisponibilité</term>
<term>Cavité péritonéale</term>
<term>Essais cliniques comme sujet</term>
<term>Humains</term>
<term>Injections veineuses</term>
<term>Plasmodium berghei</term>
<term>Préparation de médicament</term>
<term>Rats</term>
<term>Répartition dans les tissus</term>
<term>Souris</term>
<term>Vecteurs de médicaments</term>
<term>Évaluation préclinique de médicament</term>
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<front><div type="abstract" xml:lang="en">Attachment of antibodies to the surface of liposomes was performed to confer specificity for a certain cell or organ expressing the targeted antigenic determinant. These so-called immunoliposomes are expected to be applied as targeted drug carriers. In this article, the literature concerning in vivo studies of the targeting of immunoliposomes to various sites in the body is reviewed. The anatomical, physiological, and pathological constraints and current progress are described. Moreover, perspectives on the therapeutic feasibility of this drug targeting system are discussed.</div>
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Serveur d'exploration Chloroquine

Immunoliposomes in vivo.

Immunoliposomes in vivo.

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

	Serveur d'exploration Chloroquine
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